GPT-5.1 Prompting Guide

What changes when you run a Synthflow agent on GPT-5.1

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GPT-5.1 introduces several meaningful differences from the GPT-4 model family. Read OpenAI’s GPT-5.1 prompting guide for the full reference. This page summarizes what changes when you run an agent on GPT-5.1 in Synthflow.

You can change the LLM at any time from General configuration in the agent editor.

Verbosity and persistence

GPT-5.1 can be more verbose than previous models. If you notice overly long responses, add explicit constraints to your system instructions, for example:

“Be concise. Respond in under two sentences because you are on a phone call.”

You can also reinforce persistence expectations using a dedicated instruction block:

1<persistence>
2You are an agent. Continue working until the user's query is completely resolved before ending your turn.
3Only yield when you are confident the problem is fully solved.
4Never stop due to uncertainty: research or deduce the most reasonable approach and proceed.
5Do not ask the user to confirm assumptions; choose the most reasonable assumption, continue, and document it afterward.
6</persistence>

Efficiency

1<efficiency>
2Efficiency is critical. You have a time limit.
3Plan carefully, make tool calls deliberately, and verify outputs to avoid waste.
4</efficiency>

Being explicit about efficiency helps GPT-5.1 reduce unnecessary steps, retries, and tool usage.

Continue until fully resolved

To reduce latency and avoid back-and-forth turn-taking, you may include a directive such as:

“Continue working until the task is fully resolved.”

GPT-5.1 typically adheres closely to this instruction.

Prompt format guidance

Structuring your prompts clearly is especially important with GPT-5.1. We recommend sectioned prompts:

  • Role
  • Instructions
  • Tools and constraints (e.g., parallel reads, sequential writes)
  • Output format and length requirements
  • Edge cases (e.g., what to do if data is missing)

Overly strict wording

GPT-5.1 follows instructions with extremely high precision. Overly rigid or contradictory language can lead to unexpected outcomes.

In addition to Markdown formatting, many teams have found that structured XML-like blocks, for example:

1<instruction_spec> ... </instruction_spec>

This helps improve instruction clarity and makes sections easier to reference and maintain.

Repetition cleanup

Before finalizing a prompt, paste it into GPT-5.1 and ask it to check for:

  • redundancy
  • conflicting instructions
  • opportunities to simplify wording

Because GPT-5.1 adheres so strictly to instructions, small contradictions in your prompt can have outsized effects.

Prompt optimizer

OpenAI provides a built-in prompt optimizer. If you’re encountering issues with your prompt, you can use the following template to request optimization:

When asked to optimize prompts, explain which specific phrases should be added or removed to elicit the desired behavior or prevent undesired behavior.
Prompt: [PROMPT]
Desired behavior: [DESIRED BEHAVIOR]
Undesired behavior: [UNDESIRED BEHAVIOR]
While keeping as much of the existing prompt as possible, what minimal edits would help the model reliably produce the desired behavior?